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The causes of AIE were cardiac arrhythmias in two patients, myocardial infarction in one, drug overdose in two, carbon monoxide poisoning in one, and respiratory failure and sepsis in one. The median time to MRI was 2.5 days. Symmetric ar eas of restricted diffusion were found in the periventricular white matter tracts (7/7 patients), the corpus callosum (6/7 patients), internal capsule (5/7 patients), and the subcortical association fibers (3/7 patients). ADC maps confirmed the restricte d diffusion. Gray matter involvement was seen in three patients, and was more prominent on conventional imaging sequences compared with diffusion-weighted imaging. A subtle decreased in mean ADC was seen in cortex. Prominent, symmetric restricted diffu sion can occur early after AIE in white matter, whereas gray matter involvement may be less prominent. Further studies involving a larger sample and serial imaging are required to confirm these preliminary findings. |
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encephalopathy,anoxic
encephalopathy,post anoxic
hypoxia
hypoxic encephalopathy
hypoxic-ischemic leukoencephalopathy
leukoencephalopathy
MRI
MRI,abnormal
MRI,ADC maps
MRI,diffusion weighted
white matter disease
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